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A new k-means procedure is developed to identify the descriptors that produce the clustering with the optimal separation among groups. It is used a combinatorial procedure to make the selection of the descriptors that minimize the objective parameted, named global variance. A main characteristic of this procedure is that it is not required that all the variables to be known for all the objects. It has been tested that this technique could be applied to medical clinical data of patients with Diabetes Mellitus Type 2 (DMT2) with underlying diseases.

Reference: Int. J. Environ. Res. Public Health 2021 Feb 17;18(4):1919. doi: 10.3390/ijerph18041919.

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Authors: Sergio Madurga, Miroslava Nedyalkova, Vasil Simeonov